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Azoospermia is an infertility condition in males characterized by the absence of sperm in ejaculation. It is broadly classified as obstructive and non-obstructive. Obstructive azoospermia occurs due to blockage in the reproductive tract preventing sperm from entering the ejaculate. Non-obstructive azoospermia is marked by impaired production of sperm. The causative factors for non-obstructive azoospermia include genes, hormonal imbalance, and injury or infection to the testicles. This disorder has a serious impact on a man’s mental well-being due to societal norms. They suffer from anxiety, depression, and shame.

Stem cell therapy has the potential to treat non-obstructive azoospermia with lasting effects. Scientists have been investigating mesenchymal stem cells (MSCs) to restore the sperm production process. MSCs can differentiate into germ cells and also exeet their paracrine effects to induce healing of the testicular tissue. They can significantly improve the microenvironment of the testicular tissue to promote sperm production. However, the quality of MSCs is integral for stem cell therapy to be effective. Advancells provides premium quality MSCs to avail the benefits of stem cell therapy in India.

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